Three months after freeing Santanico from the Titty Twister, the Gecko Brothers are still on the run; Seth and Kate are lost in Mexico; Richie and Santanico plot vengeance on the culebra Lord. "From Dusk Till Dawn: The Series" is centered around bank robber Seth Gecko (D.J. Cotrona) and his violent, unpredictable brother, Richard "Richie" Gecko (Zane Holtz), who are wanted by the FBI and Texas Rangers Earl McGraw (Don Johnson) and Freddie Gonzalez (Jesse Garcia) after a bank heist leaves several people dead. While on the run to Mexico, Seth and Richie encounter former pastor Jacob Fuller (Robert Patrick) and his family, whom they take hostage. Using the family RV to cross the border, chaos ensues when the group detours to a strip club that is populated by vampires. They are forced to fight until dawn in order to get out alive. The series deepens the tone and expands the storyline of the film, adds new characters and backstories and explores the Mesoamerican mythology behind the creatures inside the club.